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br Results br Discussion Dopamine regulates behavioral
2024-02-21
Results Discussion Dopamine regulates behavioral responses to nicotine in Drosophila (Bainton et al., 2000), but neurochemical measurements of dopamine after nicotine stimulation had not been made. Here, we demonstrate for the first time that the stimulation of nAChRs causes dopamine release i
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The central problem in amnesia developing
2024-02-21
The central problem in amnesia developing following impairment of long-term memory consolidation or reconsolidation is a question of the underlying mechanisms, whether it is caused by impairment of retrieval or memory storage mechanisms [3,8,9,[15], [16], [17], [18]]. To answer this question, severa
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br Introduction S http www apexbt
2024-02-21
Introduction Systemic lupus erythematosus (SLE) is a group of systemic autoimmune disorders characterized by anti-nuclear GDC-0994 (ANA), rashes and photosensitivity, joint inflammation, nephritis, and other clinical criteria. SLE develops through the breakdown of three major checkpoints: adapti
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Among the AXL positive tumors that we
2024-02-21
Among the AXL-positive tumors that we screened, the TNBC cell line MDA-MB-231 showed the highest AXL expression level. Additionally, AXL protein levels were higher in TNBC patient samples than in other breast cancers. Considering the difficulty of, and the urgent need for, effective treatments of TN
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br Conclusion br Acknowledgments This research has been supp
2024-02-21
Conclusion Acknowledgments This research has been supported by the Ratchadaphiseksomphot Endowment Fund 2013 of Chulalongkorn University (CU-56-341-AS) and the Ratchadapiseksompotch Fund (RA55/22), Faculty of Medicine, Chulalongkorn University. The authors commemorate the 100th Anniversary of
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Our results suggest that plasma membrane and a containing
2024-02-21
Our results suggest that plasma membrane and a3-containing V-ATPases represent an important and novel target in the development of drugs to limit breast cancer metastasis. That knock-down of a3 has been shown to reduce metastasis of melanoma cells in an in vivo mouse model suggests that this role ma
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Comparison of the GLUT positive plus ACLY negative
2024-02-21
Comparison of the GLUT1-positive plus ACLY negative group with the GLUT1-negative plus ACLY positive group indicated no significant difference with respect to disease-free survival and overall survival. However, some obvious differences in histological types were found in their formation. A previous
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The apoptosis promoting Bcl family includes BH
2024-02-21
The apoptosis-promoting Bcl-2 family includes BH3-only proteins (e.g., Bim, Bid and Bad) and multiple-domain proteins (e.g., Bax and Bak). At the time of apoptosis stimulation (e.g., DNA damage), only the BH3-only protein is activated, directly or indirectly promoting Bax/Bak oligomerization, changi
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Furthermore different s http www apexbt com media diy
2024-02-21
Furthermore, different studies have described the APP as useful biomarkers in monitoring the post-ovariohysterectomy period in bitches with pyometra [12,14,52,53], similar to what was observed in queens in the present study. In our study, significant decreases in concentrations of a major (SAA) and
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Regarding progression free survival analyzing clinical trial
2024-02-21
Regarding progression free-survival, analyzing 12 clinical trials, we demonstrated that the use of antiangiogenic treatment results in a statistically longer PFS with a pooled HR of 0.76 (95% CI 0.65–0.89, pCinchonidine of improvement of PFS only is that after antiangiogenic therapy glioblastomas a
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br Does TIPARP contribute to the diverse species sensitivity
2024-02-20
Does TIPARP contribute to the diverse species sensitivity to TCDD toxicity? In chick embryo hepatocytes TIPARP was reported to mediate the TCDD-dependent suppression of hepatic gluconeogenesis, by reducing cellular NAD+ levels and reducing PCK1 expression, suggesting that ADP-ribosylation enhance
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Although our data show that
2024-02-20
Although our data show that agrin accelerates the innervation of engineered muscle tissue following implantation, there are still several issues that need to be considered. First, the use of primary muscle stem or progenitor p2y inhibitor (satellite cells) instead of an immortalized muscle cell lin
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To date the molecular responses of AChE have
2024-02-20
To date, the molecular responses of AChE have been partially analyzed in its mRNA level or protein activity in aquatic animals. To understand the correlation between transcriptional change and activity of AChE, we conducted both experiments in B. koreanus. Generally, the npy receptor patterns of th
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Mistletoe is universal name for various
2024-02-20
Mistletoe is universal name for various species of parasitic plant which grows attached to and within the branches of host trees such as apple, elm, oak and pine. Mistletoe extract prepared from Viscum album, a species of mistletoe in the family Santalaceae, is generally known as European mistletoe
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Several approved and or experimental drugs
2024-02-20
Several approved and/or experimental drugs, together with natural compounds, have been reported to induce autophagy in different cancer types [70], [71], [72] (Table 1). In the next paragraphs, we will review more in detail a group of these agents selected in relation to their promising future outco
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