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N-(p-amylcinnamoyl) The following are the supplementary data
2018-11-09
The following are the supplementary data related to this article. Author Contributions Competing Financial Interests Acknowledgments We thank Mr. K. Howell and K. Johnson for help with animals, Mr. L. Charalambous for generating kymographs, and Mr. T. Christensen for help with EM. This res
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A previous study on the risk factors
2018-11-09
A previous study on the risk factors in SOT recipients for developing chronic hepatitis after acute HEV infection revealed that the recipients who developed chronic hepatitis had significantly lower counts of leukocytes, total lymphocytes, platelets, and CD2, CD3, and CD4 lymphocytes than transient
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br Materials and methods br Results br Discussion The
2018-11-08
Materials and methods Results Discussion The result of phytochemical screening revealed the overwhelming presence of flavonoids in the ethylacetate extract of A. cepa tunic (ACTE). The finding is in agreement with previous works [22,23] which showed that ethylacetate fractions contain high
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bethanechol chloride Several studies have shown a complex pa
2018-11-08
Several studies have shown a complex pattern of Ahr expression during early mouse embryogenesis. Fertilized eggs at the 1-cell stage show detectable levels of Ahr mRNA (Dey and Nebert, 1998; Wu et al., 2002) and high levels of AHR activity, as determined by an elevated constitutive mRNA level of the
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Vacuolar ATPases V ATPases are large
2018-11-08
Vacuolar ATPases (V-ATPases) are large multi-subunit complexes that are organized into V0 and V1 domains, which operate by a rotary mechanism (Forgac, 2007). V-ATPase-driven proton pumping and organellar acidification are essential for vesicular trafficking along both the exocytotic and endocytotic
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There are limitations to in
2018-11-08
There are limitations to in vitro studies, the reductionist approach of focusing on a single stem cell type precludes the 5-aminosalicylic acid to gestational hypoxia that has been shown to occur over longer periods of time and precludes TSC interaction with many fetal and maternal cell types (Chakr
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When the number of stem cells
2018-11-08
When the number of stem diltiazem hcl is reduced as a consequence of damaging stimuli, physiological aging or following serial transplantation in subsequent recipients, an incomplete filling of the empty niches occurs (Albright and Makinodan, 1976; Lajtha and Schofield, 1969). By introducing extra-d
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br Myocardial regeneration after allogeneic stem cell
2018-11-08
Myocardial regeneration after allogeneic stem cell therapy Moreover, as outlined above, a consensus is gaining ground that most of the favourable effects of cell transplantation protocols used until now exert their beneficial effect by a paracrine mechanism of the transplanted ML 786 dihydrochlor
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br Resource details To generate the human iPSC line N
2018-11-08
Resource details To generate the human iPSC line, N44SV.5, non-integrative Sendai viruses containing the reprogramming factors Oct3/4, Sox2, cMyc, Klf4 have been employed (Takahashi et al., 2007). For this purpose, commercially available fibroblasts from a healthy juvenile donor were acquired in
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br Materials and methods br Acknowledgments We
2018-11-08
Materials and methods Acknowledgments We thank Dr. Keisuke Okita and Prof. Shinya Yamanaka for providing the reprogramming plasmids. Additionally, we would like to thank Tina Christoffersen and Birgit Kassow for skillful technical assistance. We acknowledge SHARE\'s Cross Faculty PhD Initiativ
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CBP is implicated in different biological
2018-11-08
CBP is implicated in different biological functions with an essential role in maintaining normal germ cells development. CBP is expressed in primordial germ cells (PGCs) and in ESCs but is highly expressed in PGCs compared with ESCs. Proper levels of CBP have been shown to be important for hematopo
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Transforming growth factor TGF signaling
2018-11-08
Transforming growth factor β (TGF-β) signaling is closely related to DNA damage repair regulation (Mitra et al., 2013). Studies have shown that TGF-β signaling can suppress BRCA1-dependent repair of DSBs (Dubrovska et al., 2005). Activin A, a member of the TGF-β superfamily of cytokines, interacts w
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Potential sources of NSCs include cell lines pluripotent
2018-11-08
Potential sources of NSCs include cell lines, pluripotent stem cell-derived NSCs, and primary NSCs harvested from fetal or adult animals. Some immortalized NSC lines can engraft and migrate extensively (Snyder et al., 1995), but they may have unstable genomes or pose a risk of tumorigenesis (Koso et
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Cancer cells use epigenetic mechanisms to
2018-11-08
Cancer (±)-Nutlin-3 use epigenetic mechanisms to control tumor growth, invasion, and resistance to therapy. Novel therapeutic approaches targeting epigenetic modifications are considered the new frontier in cancer therapy. In fact, pharmacological modulation of epigenetic alterations is expected to
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Embryonic stem cell protocols frequently employ irradiated M
2018-11-08
Embryonic stem cell protocols frequently employ irradiated MEFs as feeder cultures (Conner and fibroblast, 2001). We plated mouse embryonic stem (ES) polycomb repressive complex either with or without feeders and compared ALP expression in both cultures using our multiplexed luminescence method. Hi
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