• Alternatively the elastic wave velocities Vs and

  2018-11-05

  

  Alternatively, the elastic wave velocities (Vs and Vp in km/s) of the Rw at certain P-T condition can be readily calculated by using its corresponding shear modulus (G; GPa), adiabatic bulk modulus (KS; GPa) and density (ρ; g/cm3), according to the following equations:and With its G0, KS0 and ρ0 (G

• br Conclusions br Acknowledgements Dr

  2018-11-05

  

  Conclusions Acknowledgements Dr. Mao Q. and Mr. Rong H. are thanked for the EPMA analyses. Prof. Li Q. L. is thanked for the zircon SIMS U-Pb dating. Critical comments on the early version by Prof. Santosh M. improved the paper greatly. Two anonymous reviewers and Prof. Sun W. D. are thanked f

• Additional applications for organ on a chip devices are expa

  2018-11-05

  

  Additional applications for organ-on-a-chip devices are expansive, including the assessment of environmental toxin (National Academies, 2014), modeling of disease progression and treatment (Bhatia and Ingber, 2014; Huh et al., 2012), the advancement of personalized medicine through the improvement o

• mmp inhibitor br Conclusions The following are the

  2018-11-05

  

  Conclusions The following are the supplementary data related to this article. Author Contributions Conflict of Interest Acknowledgements This work was supported by the Health Research Institute of University Hospital Clínico San Carlos, “Generalitat Valenciana” (PROMETEOII/2014/065), by

• Epigenetic alterations are suggested to regulate gene expres

  2018-11-05

  

  Epigenetic alterations are suggested to regulate gene expression without affecting the Atglistatin sequence. These modifications include genomic DNA-methylation, histone modifications, chromatin remodeling and miRNA/non-coding RNA-induced regulation of gene expression (Hauptman and Glavac, 2013; Por

• A final model is presented to suggest that the

  2018-11-05

  

  A final model is presented to suggest that the altered microbial composition of the -infected bile duct may promote tumor development. Specifically, the authors propose that infection and colonization of bile ducts with fosters a carcinogenic microenvironment through bacterial metabolic activity,

• The following are the supplementary data

  2018-11-05

  

  The following are the supplementary data related to this article. Potential conflicts of interest Author contributions Acknowledgements This work was supported by the Defense Advanced Research Projects Agency (DARPA) grant N66001-11-1-4180 and the Wyss Institute for Biologically Inspired E

• energy metabolism Although we are investigating potential li

  2018-11-05

  

  Although we are investigating potential links between these findings and currently hypothesized models of MS pathobiology, ERY studies in MS patients are not without precedence. A report in the 1960s (Raczkiewicz and Leyko, 1966) documented enhanced production of “adenine nucleotides” from ERYs of M

• cftr We also examined Smad as

  2018-11-05

  

  We also examined Smad7 as an important regulator of the TGF-β signaling pathway as it inhibits phosphorylation of Smad2 by the TGF-β receptors, thereby acting as a negative feedback loop in this pathway to prevent deregulation. Without Smad7, TGF-β receptor activation cannot be inhibited -explaining

• br Conclusions We implemented the scattering

  2018-11-05

  

  Conclusions We implemented the scattering-integral-based full waveform inversion (FWI) concept presented in Schumacher et al.  [11] in form of the modularized software package ASKI—Analysis of Sensitivity and Kernel Inversion. In casr to monolithic software realizations of FWI, which are still c

• br Epidemiology of IFL A study using a

  2018-11-05

  

  Epidemiology of IFL A study using a representative population sample based on a census of Sao Paolo, Brazil evaluated the distribution of IFL in asymptomatic versus symptomatic subjects [34]. The goal was to define how much IFL exists in the general population and to determine a threshold beyond

• Perimenopausal and postmenopausal women usually sleep less t

  2018-11-05

  

  Perimenopausal and postmenopausal women usually sleep less; they have more insomnia and more necessity of medication to sleep than those premenopausal ones [8]. However, they usually do not talk to their doctors voluntarily and the health providers do not ask about aspects related to it. Insomnia, n

• gtpase inhibitor In inverse problem solutions different opti

  2018-11-05

  

  In inverse problem solutions, different optimization techniques are used to estimate time dependent parameters, often related to root searching iterative methods belonging to the family of steepest descent and scaled steepest descent methods. Textbook [34] present general methods of solution of inve

• with br Experimental design materials and methods We used a

  2018-11-03

  

  Experimental design, materials and methods We used a set of primer-pairs to survey for the presence/absence of with involved in OTA and FB2 biosynthesis in A. niger/A. welwitschiae strains [1], which were collected from dried fruits (n=19), Brazil nuts (n=30), coffee beans (n=27), grapes (n=40),

• br Conflict of interest br Acknowledgements This

  2018-11-03

  

  Conflict of interest Acknowledgements This research was funded by the Research Council of KU Leuven (OT/12/044) and the Research Foundation Flanders (G0920.12). Maaike Vandermosten is postdoctoral fellow of the Research Foundation Flanders. Sophie Dandache is gratefully acknowledged for partic

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