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The mechanism of hepatoprotection by methanolic extracts of
2018-10-22
The mechanism of hepatoprotection by methanolic extracts of C. hystrix and C. maxima (Red & White) FHPI is due to their antioxidant potential. This suggests that leaf extracts can reduce ROS that may lessen the oxidative damage to the hepatocytes and improve the activities of the liver antioxidant
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A potential detection method is to analyze the air
2018-10-22
A potential detection method is to analyze the air within a grain mass for specific volatile compounds (VOCs) released by insects. In recent years, headspace solid phase microextraction (HS-SPME) in conjunction with gas chromatography–mass spectrometry (GC–MS) has been employed to examine volatile c
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br Conclusion Pu erh extracts showed a
2018-10-22
Conclusion Pu-erh extracts showed a strong protection effect against the hepatic damage by oxidative stress. The protection mechanism of Pu-erh extracts is confirmed in the study via the activation of the hepatic antioxidant system and the reversal of lipid peroxidation. In addition, Pu-erh tea e
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Previous studies demonstrated SPION labeling in a variety of
2018-10-22
Previous studies demonstrated SPION-labeling in a variety of human (Niemeyer et al., 2010; Song et al., 2007) and animal (Rice et al., 2007; Zhu et al., 2007) stem cells. We used SPION to track MSC in the QUIN model. SPION were internalized in MSC without affecting cellular viability. These data cor
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br Material and methods br Results br
2018-10-22
Material and methods Results Discussion The expression of SVCT transporter has been studied in osteoblast (Tsukaguchi et al., 1999), MC3T3-E1 (Fujita et al., 2001), and articular cartilage (Clark et al., 2002; McNulty et al., 2005) but there are no data until now on ascorbic MDV3100 manufac
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Expanded BMSC here underwent intramembraneous bone formation
2018-10-22
Expanded BMSC here underwent intramembraneous bone formation on β-TCP, based on an apparent absence of a cartilage intermediate, in line with previous reports (Krebsbach et al., 1997; Martin et al., 1997; Mendes et al., 2002, 2004). Unless subjected to chondrogenic pre-induction, BMSC/β-TCP construc
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br Results and Discussion In order to
2018-10-22
Results and Discussion In order to identify regulators of ISC behavior, we carried out a screen using esgGal4 in the posterior midgut. From this screen, Dbr was identified as a candidate. Single esg+ cells are interspersed in young flies (Figure 1A). In aged flies, esg+ cells are clustered, enlar
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The adventitia of large vessels is highly vascularized
2018-10-22
The adventitia of large vessels is highly vascularized. As such, we are not surprised that our multi-parameter analytical flow cytometric analysis revealed a relatively high prevalence of Phenyl sulfate expressing surface markers consistent with the endothelial lineage, namely CD31. We also detected
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The environment in the postnatal
2018-10-22
The environment in the postnatal cerebral cortical may not be permissive for all lineage-reprogrammed astroglial iap apoptosis to differentiate into iNs. In fact, after transplantation in the neurogenic subventricular zone, we observed that both cerebellar and cortical astroglia nucleofected with A
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In our study ERK and
2018-10-20
In our study, ERK and JNK inhibitors effectively inhibited the migration of glioma ldk378 while the effect of the p38 inhibitor was not as significant. Hence, we further evaluated the effect of downregulation of uPAR and cathepsin B on the expression of ERK and JNK. Reduction in the expression leve
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In the present study we
2018-10-20
In the present study, we introduce a novel cell surface protein, CD98, that is specifically expressed on the cells of the basal layer and, in addition, remains stably expressed after a multitude of proteolytic treatments. We show that purified CD98high cells are able to induce tumor growth upon seri
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Introduction The generation of an organ requires strict cont
2018-10-20
Introduction The generation of an organ requires strict control of the number and identity of cells generated during development. Zac1 (also known as Plagl1) belongs to an imprinted gene network (IGN), which has been shown to control embryonic growth (Varrault et al., 2006). Accordingly, Zac1 knock
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br Resource table Resource details
2018-10-20
Resource table. Resource details RCe008-A (RC-4) was derived from a fresh Phenformin that was surplus to requirement or unsuitable for clinical use. The cell line was derived by whole embryo outgrowth on a chemically defined matrix consisting of laminin, fibronectin, Collagen IV and vitronectin
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br Materials methods The derivation and culturing conditions
2018-10-20
Materials & methods The derivation and culturing conditions of hAT-MSCs are thoroughly described in Supplementary Materials and methods section, while details regarding hiPS lines generation and validation are described elsewhere (Kyrkou et al., in press). Results Discussion Human AT-MSCs
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tolterodine tartrate br Resource table br Resource
2018-10-20
Resource table Resource details Multiple endocrine neoplasia type 1 (MEN1) (also termed Wermer syndrome) is an autosomal dominant hereditary which is caused by mutations on the tumor suppressor gene MEN1. MEN1 is characterized by tumorigenesis mainly in endocrine organs including parathyroid g
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