• In primary diagnosis IKZF status was not taken into

  2019-05-14

  

  In primary diagnosis IKZF1 status was not taken into account for risk group stratification. According to protocol ALL-MB-2002 regulations, risk was underestimated and patient was assigned to the SRG. Prognostic value of IKZF1 alterations in ALL, especially BCR-ABL1 negative ALL, is still debated [19

• OS is Executive Director of

  2019-05-14

  

  OS is Executive Director of the INDEPTH Network. PB is Director of the WHO Collaborating Centre for Verbal Autopsy and chairs the Scientific Advisory Committee of the INDEPTH Network. The INDEPTH Network is grateful for core funding from Sida, the Wellcome Trust, and the William & Flora Hewlett Foun

• Dinoprostone has been administered either vaginally or

  2019-05-14

  

  Dinoprostone has been administered either vaginally or intracervically, rather successfully and without serious side effects in normal pregnancies. The most important adverse reaction of dinoprostone is uterine hyperstimulation. The incidence of uterine hyperstimulation ranged from 5% to 16% in pati

• br Approval statement br Role of the

  2019-05-14

  

  Approval statement Role of the funding source Conflict of interest Acknowledgments Introduction Osteosarcoma (OS) is the most common malignancy of bone, mainly affecting children, adolescents and young adults. According to the American Cancer Society, 750–900 new cases of OS are diagn

• T-5224 Introduction Multiple myeloma MM is the most

  2019-05-14

  

  Introduction Multiple myeloma (MM) is the most frequent cancer to involve the skeleton with 80–90% of patients developing bone lesions during their disease course [1]. Myeloma bone lesions are purely osteolytic and are associated with severe and debilitating bone pain, pathologic fractures, hyperca

• br Discussion In Brugada syndrome BrS

  2019-05-14

  

  Discussion In Brugada syndrome (BrS), ICD buy 69 8 is recommended for patients experiencing VF. However, up to 48% of such high-risk patients experience frequent ICD shocks [1] that result in significant sequelae such as depression, post-traumatic stress, and difficult VF termination due to a re

• Con esto no se pretende se

  2019-05-14

  

  Con esto no se pretende señalar que en el terreno educativo no existan mentes lúcidas o que sus actores se comporten con una meridiana ingenuidad. Solamente queremos advertir que la constante necesidad de mejorar la educación y de aggiornar sus procesos CA-074 Me la dinámica cambiante de la sociedad

• Declaration of interests br Abstract Background In times of

  2019-05-13

  

  Declaration of interests Abstract Background In times of seawater inundation in coastal deltas, unprotected drinking water sources, such as ponds and shallow tube wells, take on salt water with each inundation. Daily consumption of these saline sources contributes to overall sodium intake. Altho

• Adequate nutritional support for pregnant women is

  2019-05-13

  

  Adequate nutritional support for pregnant women is an important issue, not only to help such women maintain peak health and performance, but also as it indirectly affects fetal growth and the minimization of adverse fetal outcome risks. Among those nutritional components that are integral to this su

• br Conclusion br Conflict of interest

  2019-05-13

  

  Conclusion Conflict of interest Introduction The implantable cardioverter-defibrillator (ICD) has dramatically reduced the risk of sudden death in patients with malignant ventricular tachyarrhythmias [1,2]. However, 10–30% of patients who have undergone ICD implantation experience “electric

• Currently we are unable to fully understand

  2019-05-13

  

  Currently, we are unable to fully understand the cytochalasin d and distribution of the AT arising around the apex of the triangle of Koch. Koyama et al. closely studied the spatial and topographic variation in the distribution of this type of AT around the His-bundle [17]. As demonstrated in the p

• The findings revealed that TCZ women

  2019-05-13

  

  The findings revealed that TCZ women of 18–29 years of age had knowledge about the nature of Pap smear as compared to other categories, and they also knew that if cervical cancer was detected early, medication and other early forms of interventions could be initiated to deal with the problem before

• In an effort to determine whether the primary tumour might

  2019-05-13

  

  In an effort to determine whether the primary tumour might be responsible for “fertilising” the bone “soil” ready for the cancer “seed”, we recently found that a hypoxic gene signature, and more specifically the secreted enzyme lysyl oxidase (LOX) was closely associated with bone metastasis, specifi

• No es xito peque o

  2019-05-13

  

  No es éxito pequeño que “bajo la dirección del maestro Stols” (así indica el colofón del libro) se lograse tal parecido con ellas, pero conviene subrayar que Jusep Torres Campalans no es mera mímesis material de la colección Le goût de notre temps sino también, o ante todo, estructural. El Picasso d

• In Richard Walker and colleagues report the results of

  2019-05-13

  

  In , Richard Walker and colleagues report the results of a case-control study of risk factors for stroke in Tanzania. Their study makes several important contributions. First, they provide the first information about importance of risk factors for stroke in urban and rural Tanzania, and confirm the

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