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Introduction Multiple myeloma MM is the most frequent cancer
2019-05-15
Introduction Multiple myeloma (MM) is the most frequent cancer to involve the skeleton with 80–90% of patients developing bone lesions during their disease course [1]. Myeloma bone lesions are purely osteolytic and are associated with severe and debilitating bone pain, pathologic fractures, hyperca
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We examined pharmacologic exposures among the subset of wome
2019-05-15
We examined pharmacologic exposures among the subset of women diagnosed with breast cancer on or after 1995 (N=620) and found that over two thirds (70.8%) received adjuvant endocrine therapy prior to hip or opioid receptor antagonist fracture, including 30.8% who received tamoxifen only, 23.1% who
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br Material and methods br Results
2019-05-15
Material and methods Results Discussion The present study found that the plasma BNP level was higher in patients with LAA thrombus than in those without LAA thrombus. Additionally, the BNP level was negatively associated with peak LAA velocity evaluated using TEE and positively associated w
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Lastly it is equally important to mention that the microenvi
2019-05-14
Lastly, it is equally important to mention that the microenvironment and genetic background of the host with a previous history of two independent malignancies may have further facilitated the selective proliferation of a clone with trisomy 11 [9,10], while normal SBI-0206965 suffered proliferative
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In primary diagnosis IKZF status was not taken into
2019-05-14
In primary diagnosis IKZF1 status was not taken into account for risk group stratification. According to protocol ALL-MB-2002 regulations, risk was underestimated and patient was assigned to the SRG. Prognostic value of IKZF1 alterations in ALL, especially BCR-ABL1 negative ALL, is still debated [19
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OS is Executive Director of
2019-05-14
OS is Executive Director of the INDEPTH Network. PB is Director of the WHO Collaborating Centre for Verbal Autopsy and chairs the Scientific Advisory Committee of the INDEPTH Network. The INDEPTH Network is grateful for core funding from Sida, the Wellcome Trust, and the William & Flora Hewlett Foun
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Dinoprostone has been administered either vaginally or
2019-05-14
Dinoprostone has been administered either vaginally or intracervically, rather successfully and without serious side effects in normal pregnancies. The most important adverse reaction of dinoprostone is uterine hyperstimulation. The incidence of uterine hyperstimulation ranged from 5% to 16% in pati
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br Approval statement br Role of the
2019-05-14
Approval statement Role of the funding source Conflict of interest Acknowledgments Introduction Osteosarcoma (OS) is the most common malignancy of bone, mainly affecting children, adolescents and young adults. According to the American Cancer Society, 750–900 new cases of OS are diagn
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T-5224 Introduction Multiple myeloma MM is the most
2019-05-14
Introduction Multiple myeloma (MM) is the most frequent cancer to involve the skeleton with 80–90% of patients developing bone lesions during their disease course [1]. Myeloma bone lesions are purely osteolytic and are associated with severe and debilitating bone pain, pathologic fractures, hyperca
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br Discussion In Brugada syndrome BrS
2019-05-14
Discussion In Brugada syndrome (BrS), ICD buy 69 8 is recommended for patients experiencing VF. However, up to 48% of such high-risk patients experience frequent ICD shocks [1] that result in significant sequelae such as depression, post-traumatic stress, and difficult VF termination due to a re
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Con esto no se pretende se
2019-05-14
Con esto no se pretende señalar que en el terreno educativo no existan mentes lúcidas o que sus actores se comporten con una meridiana ingenuidad. Solamente queremos advertir que la constante necesidad de mejorar la educación y de aggiornar sus procesos CA-074 Me la dinámica cambiante de la sociedad
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Declaration of interests br Abstract Background In times of
2019-05-13
Declaration of interests Abstract Background In times of seawater inundation in coastal deltas, unprotected drinking water sources, such as ponds and shallow tube wells, take on salt water with each inundation. Daily consumption of these saline sources contributes to overall sodium intake. Altho
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Adequate nutritional support for pregnant women is
2019-05-13
Adequate nutritional support for pregnant women is an important issue, not only to help such women maintain peak health and performance, but also as it indirectly affects fetal growth and the minimization of adverse fetal outcome risks. Among those nutritional components that are integral to this su
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br Conclusion br Conflict of interest
2019-05-13
Conclusion Conflict of interest Introduction The implantable cardioverter-defibrillator (ICD) has dramatically reduced the risk of sudden death in patients with malignant ventricular tachyarrhythmias [1,2]. However, 10–30% of patients who have undergone ICD implantation experience “electric
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Currently we are unable to fully understand
2019-05-13
Currently, we are unable to fully understand the cytochalasin d and distribution of the AT arising around the apex of the triangle of Koch. Koyama et al. closely studied the spatial and topographic variation in the distribution of this type of AT around the His-bundle [17]. As demonstrated in the p
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