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Two other groups subsequently published further data on iPSC
2019-05-29
Two other groups subsequently published further data on iPSCs models of ARVC that have improved our understanding of this disease. Kim et al. developed iPSC models using episomal methods from 2 ARVC patients, as well as with PKP2 mutations . Detailed electrophysiological characterization of mutant a
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buy 4EGI-1 br Discussion Prehabilitation is a program to enh
2019-05-29
Discussion “Prehabilitation” is a program to enhance functional capacity and psychological health to enable patients to withstand an upcoming stressor, e.g. surgery. It is intended to reduce treatment-related morbidity and/or mortality, to decrease length of hospital stay and/or re-admission, an
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CA 074 br Conflict of interest br
2019-05-29
Conflict of interest Introduction Nasopharyngeal carcinoma (NPC) is a tumor arising from the epithelial cells that line the surface of the nasopharynx. It is a commonly found tumor of the head and neck region in adults, and its incidence varies widely in different regions. It has been observe
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dna methyltransferase br Materials and methods br Results br
2019-05-29
Materials and methods Results Discussion Utilizing IHC, the majority of OS samples were positive for RANKL (68%), with RANKL staining detectable in OS tumor dna methyltransferase and tumor anaplastic cells. However, a wide range of RANKL expression within the OS component was observed and
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br Discussion br Conclusions br
2019-05-29
Discussion Conclusions Conflicts of interest Introduction Catecholaminergic polymorphic ventricular tachycardia (CPVT) is induced by emotional stress or exercise in patients without organic heart disease and may be polymorphic or bidirectional (Fig. 1) [1–3]. This ventricular arrhythmia
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It is important to know whether pilsicainide can be
2019-05-28
It is important to know whether pilsicainide can be used as a therapeutic agent for LQT2 patients; and if so, we should determine the types of LQT2 mutation carriers to whom pilsicainide could be administered. As shown in Fig. 8, we examined the effects of pilsicainide on two mutant hERG proteins, G
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myeloperoxidase br Although much attention centres on Afghan
2019-05-28
Although much attention centres on Afghanistan\'s political and security transitions, malnutrition is a foremost concern. Because an absence of adequate nutrition has crucial long-term effects on individuals and on social and economic development, nutrition rates in Afghanistan deserve attention a
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Hablar del movimiento posmoderno parece haberse convertido
2019-05-28
Hablar del movimiento posmoderno parece haberse convertido en un lugar común. Un movimiento artístico, cultural o filosófico que se escape Homoharringtonine las expectativas de lo preestablecido suele denominarse rápidamente “posmoderno” sin indagar con profundidad cuáles son las características qu
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As del tercer tomo con
2019-05-28
Así, del tercer tomo, con su proyecto y horizonte interpretativo conjunto, debemos rescatar la forma de dar cuenta de las formulaciones artísticas (literarias en este caso, pero fácilmente extrapolables) como parte de una empresa sociopolítica, englobadora de lo cultural, en la cual se destaca al su
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In summary Welch and colleagues review is important Not
2019-05-28
In summary, Welch and colleagues\' review is important. Not all systematic reviews on the same topic reach the same conclusion, but the convergence between the Campbell and Cochrane reviews here could hardly be stronger. The additional network and subgroup analyses in the Campbell review find no evi
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br Conclusion br Conflict of interest br
2019-05-28
Conclusion Conflict of interest Introduction Loss-of-function mutations in the cardiac sodium (Na+) channel gene have been implicated in Brugada syndrome, progressive cardiac conduction defect (PCCD), sick sinus syndrome, and idiopathic ventricular fibrillation (IVF) [1]. In the present stu
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br Methods As we were not privy to
2019-05-28
Methods As we were not privy to the median year of enrolment, for all selected studies, the mean enrolment year ([start of enrolment+end of enrolment]/2) was calculated. If these dates were unavailable, the corresponding authors or sponsoring companies were contacted. When all methods to gather t
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BB-94 Preference for injectable therapy over oral therapy co
2019-05-28
Preference for injectable therapy over oral therapy [17], contrary to our findings from a previous study [18], could reflect the fact that most patients have not received an oral bone-targeted agent for metastatic disease. However, the practical advantages of an injectable therapy and the lack of ne
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br Discussion In the present case dyssynchronization between
2019-05-28
Discussion In the present case, dyssynchronization between the atrial and ventricular beats resulted in abnormal pacing spikes detected on the surface electrocardiogram, and it is a potentially life-threatening condition. Previous case reports have suggested that this condition might be caused by
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br In Sanguinetti et al and Barhanin
2019-05-28
In 1996, Sanguinetti et al. and Barhanin et al. independently found that, when coassembled with the accessory subunit KCNE1, the KCNQ1 and KCNE1 complex could form a channel that very closely exhibited conductive and kinetic properties similar to that of cardiac IKs[14,56]. Kass and coworkers subs
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