• Neuropsychological studies of adults with problem gambling i

  2019-09-29

  

  Neuropsychological studies of adults with problem gambling indicate impairments in many cognitive areas including inhibition, working memory, decision-making, cognitive flexibility, and executive planning (Ledgerwood et al., 2012, Goudriaan et al., 2006). Dopamine is a neurotransmitter that regulate

• Introduction Prolyl hydroxylation is a widely observed post

  2019-09-29

  

  Introduction Prolyl hydroxylation is a widely observed post translational modification in collagen, an abundant animal protein. The high content (~13% per chain of the triple helical structure) of 4-hydroxyproline (Hyp,O) in collagen, togather with the natural abundance of collagen has led to the e

• With regards to what might represent a typical baseline ChE

  2019-09-29

  

  With regards to what might represent a typical “baseline” ChE (or AChE) activity in Saccostrea sp., it metforman should be remembered that the observed enzyme responses were obtained in laboratory exposures, over a narrow experimental window (96h), with specimens collected over the course of a week

• The upregulation of PTGS and PTGS in late

  2019-09-29

  

  The upregulation of PTGS1 and PTGS2 in late gestation in mares could be linked to the high levels of estrogens produced by the fetoplacental unit. Estrogens are thought to be effective stimulators of prostaglandin production by potentially up regulating PTGS2 expression. Although a recent publicatio

• br Experimental br Results and discussion

  2019-09-29

  

  Experimental Results and discussion On the basis of the information obtained from the studies on RHA/TiO2 nanocomposites, it Epibrassinolide is expected that this reagent can be used as a catalyst for the promotion of the organic reactions. So this reagent was used in the promotion of the con

• br Results and discussion br Conclusions In conclusion

  2019-09-27

  

  Results and discussion Conclusions In conclusion, we have developed rational strategies that allowed us to successfully identify a series of novel analogs structurally related to to modulate the activity of estrogen-related receptors (ERRγ and ERRβ), which are constitutively active. All of the

• In this report we evaluate if this molecular mechanism

  2019-09-27

  

  In this report, we evaluate if this molecular mechanism is used universally by high-fidelity DNA polymerases during the replication of DNA lesions that are structurally distinct from abasic sites. This was approached by quantifying the kinetic parameters for the incorporation of modified and non-nat

• mg115 Herein we explored by docking

  2019-09-27

  

  Herein, we explored by docking studies the effectiveness of replacing the dimethyl substitution at C (6) of dihydrotriazine with a folded azaspiro-containing substituent, along with the introduction of differently substituted phenyl- and benzyl-rings or alkyl chains, linked at the position 1 of the

• br Conclusion br Introduction Biological wastewater

  2019-09-27

  

  Conclusion Introduction Biological wastewater treatment is targeted towards the removal of phosphorous, nitrogen and organic substances by the metabolic activity of a diverse activated sludge microbial community. More precisely, it is based on the versatile catalytic activity of the microbial

• Previous studies demonstrated that cPLA translocates

  2019-09-27

  

  Previous studies demonstrated that cPLA2α translocates to the phagosomal membrane during macrophage phagocytosis through mechanisms that, in humans, involve phosphorylation of the enzyme by c-Jun N-terminal kinases and membrane association via the cationic cluster of four lysine residues present at

• br Materials and methods br Results and

  2019-09-27

  

  Materials and methods Results and discussion Concluding remarks Enzymatic production of bioactive 9-cis-11-trans-conjugated linoleic Index Kit 1 is part of a detoxification mechanism against linoleic acid which is a toxic and stress factor for many lactic bacteria such as Lactobacillus pla

• br Experiments and Methods br Results and

  2019-09-26

  

  Experiments and Methods Results and Discussion Conclusions Here, the interactions between two newly-synthesized carbazole derivative—cationic δ,δ′‑diazacarbazoles and DNA were characterized by several spectroscopic means, including UV–Vis and fluorescence, AFM and fluorescence imaging. The

• Addition of deoxyuridine to CY cultures led to a significant

  2019-09-26

  

  Addition of deoxyuridine to CY11 cultures led to a significant decline in the amount of uracil-DNA (Fig. 5). Deoxyuridine effectively induces the deo operon and is efficiently degraded to uracil and deoxyribose 1-phosphate by the deoA gene product, thymidine phosphorylase; a minor percentage of deox

• br Genotype phenotype correlations Genotype phenotype correl

  2019-09-26

  

  Genotype-phenotype correlations Genotype-phenotype correlations are limited. Compared with individuals with truncating variants, those with pathogenic missense variants in the adenosine triphosphate binding site had a milder disorder, some with ability to walk unaided, better hand use, and less r

• These data indicate that in the context

  2019-09-26

  

  These data indicate that, in the context of the N-terminal 42 amino acids of p53, threonine 18 is a substrate for phosphorylation by CK1 as mediated by prior phosphorylation of serine 15. To determine whether this is a property of full length p53, GST-p53 fusion proteins comprising the full length p

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