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Magnetic interactions between metal ions are usually
2021-04-15

Magnetic interactions between metal ions are usually described by superexchange via intermediate ligands. Although the general principles of the superexchange mechanism are essentially the same for d and f ions, calculations of exchange parameters for lanthanides are more difficult than for transiti
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br Related work Goal of this section
2021-04-15

Related work Goal of this section is to show related work focused on methods useful to assess the reliability of clustered COTS-based systems. Connelly et al. [1] propose an approach to delineate safety assurance for the use of COTS OS in safety-related applications, which must fall in SIL2. The
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The ACC receptor family appear
2021-04-15

The ACC receptor family appear to be attractive targets for the development of novel anthelmintics. With this in mind we also tested the activity of the anthelmintics levamisole and pyrantel which activate the nematode nAChR (Martin and Robertson, 2007). We found both molecules were partial agonists
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Bioinformatics analysis for genes encoding proteins
2021-04-15

Bioinformatics analysis for genes encoding proteins (ESR1, IL6, TERT, DNMT3B) showed that NF-kB is one of the transcription factors that might be regulating their expression, especially for IL6, TERT and DNMT3B genes. Previous studies have demonstrated that PA induces NF-kB activation, thus increasi
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Of all the residues of plants the ash obtained
2021-04-15

Of all the residues of plants, the ash obtained from the incineration of RH has highest amount of silica content [7]. The rice crop normally ingest orthosilicic Mupirocin in large quantity from ground water and this acid is further polymerized in the husk, ultimately contribute to amorphous silica [
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TgTCEA from petals TgTCEA and TgTCEB from pollen
2021-04-15

TgTCEA from petals (TgTCEA1) and TgTCEB from pollen grains (TgTCEB1) were used throughout the study. The recombinant enzymes were expressed in , and purified as the His-tag-free forms as described previously., Enzyme reactions were performed at 4 mM substrates under the same conditions as described
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br Material and methods br Results br Discussion The
2021-04-15

Material and methods Results Discussion The results show for the first time that DDRs may be involved in the pathogenic mechanisms of neurodegenerative diseases. We found that DDR1 and DDR2 levels are up-regulated in post-mortem AD and PD brains, suggesting that these receptors play a role
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To further define the importance of CYP A
2021-04-15

To further define the importance of CYP3A for OSC metabolism in vivo, a strong CYP3A inhibitor ketoconazole was used to test whether CYP3A would affect its metabolism. As expected, the biotransformation of OSC to SC was significantly decreased by ketoconazole at all three substrate concentrations. H
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The identification of CCR B cells within the
2021-04-15

The identification of CCR6+ Merimepodib australia within the LZ as direct progenitors of MBCs provides a new window into the evolution of immune responses. In practical terms, flow-cytometric detection of CCR6+ GC B cells could provide a means of rapidly assessing vaccine efficacy when applied to f
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A great deal of research has
2021-04-14

A great deal of research has focused on candidate medications to modulate dopaminergic mechanisms through which psychomotor stimulants produce addictive effects, i.e., drugs that expressly target the DA transporter, D1-like receptor, or D2-like receptors., , However, effective dopaminergic-based pha
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DNA methylation is associated with transcriptional silencing
2021-04-14

DNA methylation is associated with transcriptional silencing of tumor suppressors or other genes important for normal cellular function and plays an important role in the development of cancer and other diseases (such as breast and colorectal cancers) [19]. DNA methyltransferases (MTases) are a fami
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br Diacylglycerol kinases and T cell responses br Diacylglyc
2021-04-14

Diacylglycerol kinases and T cell responses Diacylglycerol kinases and cancer Several studies implicate DGKα in tumor progression, but its function is debated, as it might also have roles as a tumor suppressor. Diminished DGKα expression is linked to malignant transformation in epithelia. High
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Resistance to SP is linked to
2021-04-14

Resistance to SP is linked to point mutations that accumulate at several sites in the dihydrofolate reductase (dhfr) and dihydropteroate synthase (dhps) rxr receptor of P. falciparum (Roper et al., 2003). These mutations have been identified in codons 16, 51, 59, 108, and 164 in the dhfr gene and co
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The notion that a small subset of inducible
2021-04-14

The notion that a small subset of inducible cellular transcripts, encoding immunological important factors, is translocated across the nuclear envelope by the karyopherin CRM1 is gaining support from various recent studies. For example, experimental evidence has been provided demonstrating that the
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br Involvement of p MAPK pathway The
2021-04-14

Involvement of p38 MAPK pathway The NF-κB signal transduction cascade is a major stress response signaling pathway for the COX-2 gene expression. In mice and humans, the COX-2 promoter has caspofungin for many transcription factors, including NF-κB in the 5′ region of the COX-2 gene [11], and th
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