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This study attempts to investigate the practicality of SMA a
2018-11-12
This study attempts to investigate the practicality of SMA adoption in banks in Nigeria, a developing country. More specifically, it examines whether banks in Nigeria practice SMA and the benefits SMA offers the industry. Historically, the Nigerian banking industry is known for instability, majorly
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The architects realized an appealing building
2018-11-12
The architects realized an appealing building design while taking into consideration the findings of the climate specific development and evaluation of an glycoprotein inhibitors efficient building energy concept. The section drawing of the planned house, depicted in Figure 7, shows the layer of in
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br Result br Discussion of findings The
2018-11-12
Result Discussion of findings The result of the analysis shows that the residential buildings sampled were mainly single-family bungalows of 2-bedrooms and 3-bedrooms, which of course, are the prevalent housing types in most low-density public housing schemes in Nigeria. The physical and spati
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br Literature review Older buildings across Europe are
2018-11-12
Literature review Older buildings across Europe are key constituents of the existing building stock. In the UK, traditional buildings are categorized as pre-1919 (DCLG, 2010), and according to Coles et al. (2015) these were years when building regulations were completely updated. The traditional
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The diagnosis of suspected appendicitis remains challenging
2018-11-12
The diagnosis of suspected appendicitis remains challenging to physicians or surgeons in the emergency service. The state-of-the art diagnosis of Ap involves the use of CT and ultrasonography. The accuracy of clinical diagnosis is approximately 80%, which corresponds to a negative appendectomy rate
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br Conclusion br Introduction Spigelian hernia
2018-11-12
Conclusion Introduction Spigelian hernia accounts for only about 2% of all hernias. It occurs as a defect formed in the Spigelian aponeurosis and can be congenital or acquired. In 1645, Adriann van der Spieghel, a Flemish anatomist, was the first to describe a defect in the semilunar line (lin
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br Acknowledgement br Introduction Murraya paniculata L
2018-11-12
Acknowledgement Introduction Murraya paniculata (L.) belongs to the Rutaceae family. This plant is native to areas in Southeast Asia [1], such as Southern China, Vietnam and Malay Peninsula. In China, the ornamental plant M. paniculata is widely cultivated on the sides of the road for decorati
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Fgfs activating only FGFRb isotypes had no
2018-11-12
Fgfs activating only FGFRb isotypes had no effect on the number of EpCAM+Sox17-GFPHi fdps developing in response to activin or on the number of EdU-incorporating cells. Since FGFR inhibitors reduce the numbers of Sox17-GFPHi cells (Hansson et al., 2009) we suspect that endogenous Fgf signaling is s
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br Integrins Integrins are a large
2018-11-12
Integrins Integrins are a large family of receptors which can bind ECM components, soluble extracellular ligands or other membrane bound cell surface molecules. In mammals, there are 24 known heterodimeric integrin receptors comprising of a non-covalent pairing of one of 8 β subunits with one of
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br Long term maintenance of
2018-11-12
Long term maintenance of hPSCs in a scalable and defined suspension culture system A report published recently in Stem Cell Research (Chen et al., 2012, 8:388–402) extends from these previous studies to demonstrate for the first time, the long term expansion of hESCs retaining the characteristic
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br Discussion We have described
2018-11-12
Discussion We have described an approach that achieves inducible, retrovirus-mediated gene expression by using the coding sequence of TFs fused to an ERT2 motif. Fusion of the ERT2 motif to two TFs that regulate fate-choice decisions in the course of adult neurogenesis (i.e., ASCL1 and NEUROD1) a
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It is interesting to note that in utero lethality in
2018-11-12
It is interesting to note, that in utero lethality in FAH−/− pigs, which is correctable by NTBC, provides unique opportunities to study regenerative therapies targeted to the fetus (MacKenzie et al., 2002). As liver injury can be initiated by stopping NTBC at any time in development, FAH−/− pigs cou
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It is now established that in all vertebrates studied
2018-11-12
It is now established that, in all vertebrates studied, hmg-coa reductase from the PEO encapsulate the looping heart at mid-gestation, forming the critical outer layer. The epicardium then enters a complex ‘dialogue’ with the underlying myocardium; secretes trophic factors essential for myocardial m
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br Materials and methods br Results br
2018-11-12
Materials and methods Results Discussion It is known that mutation types of SOD1 affect not only enzymatic activity and protein half-life of SOD1, but also age at onset and the survival time of SOD1-ALS patients (Hayward et al., 2002) (Borchelt et al., 1994) (Regal et al., 2006). However, t
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Homozygous GBA mutations are the
2018-11-09
Homozygous GBA1 mutations are the cause of the autosomal recessive lysosomal storage disorder Gaucher disease (GD). Both homozygous and heterozygous GBA1 mutation carriers have a similar risk for the development of PD in later life, although onset in GD patients may be earlier (Alcalay et al., 2014)
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